Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 6/20 | 0.55 |
| ▸ | JAK2 | O60674 | 5/20 | 0.55 |
| ▸ | BRD4 | O60885 | 7/20 | 0.54 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | CDK7 | P50613 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 7/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.50 |
| ▸ | RET | P07949 | 3/20 | 0.49 |
| ▸ | WEE1 | P30291 | 3/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381910 | 1.00 | JAK1 (0.55) | JAK1JAK2BRD4PTK6ERBB2 | |
| SCHEMBL25381155 | 0.92 | JAK1 (0.59) | JAK1JAK2BRD4CDK7CDK9 | |
| SCHEMBL31163053 | 0.90 | BRD4 (0.56) | JAK1JAK2BRD4CDK7CDK9 | |
| SCHEMBL25383250 | 0.84 | BRD4 (0.69) | JAK1JAK2BRD4PTK6CDK7 | |
| SCHEMBL30565217 | 0.84 | BRD4 (0.69) | JAK1JAK2BRD4PTK6CDK7 | |
| SCHEMBL25381831 | 0.84 | BRD4 (0.69) | JAK1JAK2BRD4PTK6CDK7 | |
| SCHEMBL30565221 | 0.84 | BRD4 (0.69) | JAK1JAK2BRD4PTK6CDK7 | |
| SCHEMBL10267648 | 0.84 | JAK1 (0.53) | JAK1JAK2BRD4CDK7CDK9 | |
| SCHEMBL270247 | 0.84 | BRD4 (0.54) | JAK1JAK2BRD4PTK6CDK7 | |
| SCHEMBL25381904 | 0.83 | BRD4 (0.49) | JAK1JAK2BRD4PTK6ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673149-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4486348-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2025-01-08 | — | — | EP | disclosed |
| CN-118804751-A | New compounds and treatment of renal cell carcinoma | 巴什生物技术公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024179699-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| WO-2023166153-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC (US) | 2023-09-07 | — | — | WO | disclosed |