Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.56 |
| ▸ | JAK1 | P23458 | 6/20 | 0.53 |
| ▸ | JAK2 | O60674 | 4/20 | 0.53 |
| ▸ | JAK3 | P52333 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK7 | P50613 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | BUB1B | O60566 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | WEE1 | P30291 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381155 | 0.90 | JAK1 (0.59) | BRD4JAK1JAK2JAK3CCNT1 | |
| SCHEMBL30565219 | 0.90 | JAK1 (0.55) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL25381910 | 0.90 | JAK1 (0.55) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL25381831 | 0.83 | BRD4 (0.69) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL25383250 | 0.83 | BRD4 (0.69) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL30565221 | 0.83 | BRD4 (0.69) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL30565217 | 0.83 | BRD4 (0.69) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL10267648 | 0.82 | JAK1 (0.53) | BRD4JAK1JAK2JAK3CCNT1 | |
| SCHEMBL270247 | 0.82 | BRD4 (0.54) | BRD4JAK1JAK2JAK3LRRK2 | |
| SCHEMBL31163162 | 0.81 | BRD4 (0.72) | BRD4JAK1JAK2JAK3BUB1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673149-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | Trustlife Global Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024179699-A1 | NEW COMPOUNDS AND TREATMENT OF RENAL CELL CARCINOMA | BASH BIOTECH INC. (US) | 2024-09-06 | — | — | WO | disclosed |