SCHEMBL305654

SCHEMBL305654

CC(C)[C@@H]1CC[C@](C)(C(N)=O)C[C@H]1O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.35
TRPM8 Q7Z2W7 2/20 0.35
EPHX1 P07099 2/20 0.34
ALOX5 P09917 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
FFAR3 O14843 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL305655 1.00 TRPA1 (0.35) TRPA1TRPM8EPHX1ALOX5L3MBTL1
Alcohol SCHEMBL28802614 0.94 TRPA1 (0.32) TRPA1TRPM8EPHX1
SCHEMBL28095105 0.84 TRPA1 (0.36) TRPA1TRPM8FFAR3
SCHEMBL7978202 0.84 FFAR3 (0.45) TRPA1TRPM8FFAR3
SCHEMBL7978197 0.84 FFAR3 (0.45) TRPA1TRPM8FFAR3
SCHEMBL28034706 0.83 TRPA1 (0.39) TRPA1TRPM8EPHX1FFAR3
SCHEMBL29990852 0.81 TRPA1 (0.34) TRPA1TRPM8
SCHEMBL30185795 0.81 TRPA1 (0.34) TRPA1TRPM8
Potassium Ion SCHEMBL29504220 0.81 TRPA1 (0.34) TRPA1TRPM8
SCHEMBL30034418 0.81 TRPA1 (0.34) TRPA1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240057595-A1 INSECT REPELLENT COMPOSITIONS SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2024-02-22 US claimed
WO-2022147076-A1 INSECT REPELLENT COMPOSITIONS MANUS BIO INC. (US) 2022-07-07 WO claimed
WO-2020183759-A1 DENTAL CLEANER 株式会社 東亜産業 2020-09-17 WO claimed
EP-1919279-B1 MATERIAL CONTROLLINGLY RELEASING A LIQUID ACTIVE SUBSTANCE BY EVAPORATION AND A MOSQUITO REPELLENT BRACELET COMPRISING SAID MATERIAL EVERGREEN LAND LTD (HK) 2017-01-11 EP claimed
EP-1556332-B1 COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAME GIVAUDAN SA (CH) 2016-10-05 EP claimed
CN-101365333-B Material gradually releasing liquid active substance by evaporation and mosquito repellent bracelet incorporating such material EVERGREEN LAND LTD 2014-08-13 CN claimed
CN-101616598-B Center-filled coated chewing gum and preparation method thereof LOTTE CONFECTIONERY CO LTD KR 2014-05-28 CN claimed
EP-2124601-B1 CENTER-FILLED COATED GUM AND A METHOD OF ITS PREPARATION LOTTE CONFECTIONERY CO LTD (KR) 2012-07-11 EP claimed
US-8093290-B2 Coolant solutions and compositions comprising the same GIVAUDAN SA (CH) 2012-01-10 US claimed
US-20090148528-A1 Material that progressively liberates an active liquid substance by evaporation, and mosquito repellent bracelet incorporating such a material EVERGREEN LAND LIMITED (CN) 2009-06-11 US claimed
CN-101365333-A Material gradually releasing liquid active substance by evaporation and mosquito repellent bracelet incorporating such material EVERGREEN LAND LTD (HK) 2009-02-11 CN claimed
EP-1919279-A1 MATERIAL CONTROLLINGLY RELEASING A LIQUID ACTIVE SUBSTANCE BY EVAPORATION AND A MOSQUITO REPELLENT BRACELET COMPRISING SAID MATERIAL Evergreen Land Limited (HK) 2008-05-14 EP claimed
WO-2007026082-A1 MATERIAL CONTROLLINGLY RELEASING A LIQUID ACTIVE SUBSTANCE BY EVAPORATION AND A MOSQUITO REPELLENT BRACELET COMPRISING SAID MATERIAL EVERGREEN LAND LIMITED (HK) 2007-03-08 WO claimed
CN-1300095-C Coolant solutions and compositions comprising the sameitle GIVAUDAN SA (CH) 2007-02-14 CN claimed
US-20060051301-A1 Coolant solutions and compositions comprising the same GIVAUDAN SA (CH) 2006-03-09 US claimed
CN-1692096-A Coolant solutions and compositions containing same GIVAUDAN SA (CH) 2005-11-02 CN claimed
EP-1556332-A1 COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAME Givaudan SA (CH) 2005-07-27 EP claimed
WO-2004037764-A1 COOLANT SOLUTIONS AND COMPOSITIONS COMPRISING THE SAMEITLE GIVAUDAN SA (CH) 2004-05-06 WO claimed
US-20240365771-A1 PORTABLE ACCESSORY COMPRISING A CASE FOR RECEIVING A PAD CONTAINING A VOLATILE ACTIVE SUBSTANCE EVERGREEN LAND LIMITED (CN) 2024-11-07 US disclosed
EP-0342538-A2 Smoking article with improved means for delivering flavorants R.J. REYNOLDS TOBACCO COMPANY (US) 1989-11-23 EP disclosed