Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 1.00 |
| ▸ | GUSB | P08236 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354092 | 1.00 | DGAT1 (1.00) | DGAT1GUSBCHEK2SLC2A1KDR | |
| SCHEMBL1252086 | 0.93 | DGAT1 (0.87) | DGAT1GUSBMEN1NPC1ALDH1A1 | |
| SCHEMBL1250481 | 0.93 | DGAT1 (0.86) | DGAT1GUSBCHEK2SLC2A1PTGDR2 | |
| SCHEMBL10299681 | 0.90 | DGAT1 (0.81) | DGAT1GUSBCHEK2KDR | |
| SCHEMBL1252006 | 0.88 | DGAT1 (0.78) | DGAT1GUSBCHEK2 | |
| SCHEMBL1250459 | 0.86 | DGAT1 (0.76) | DGAT1GUSBCHEK2NPC1ALDH1A1 | |
| SCHEMBL1252216 | 0.86 | DGAT1 (1.00) | DGAT1GUSBCHEK2SLC2A1PTGDR2 | |
| SCHEMBL30385298 | 0.86 | DGAT1 (1.00) | DGAT1GUSBCHEK2SLC2A1PTGDR2 | |
| SCHEMBL1252392 | 0.85 | DGAT1 (0.75) | DGAT1GUSBMEN1ALDH1A1HPGD | |
| SCHEMBL1252747 | 0.83 | DGAT1 (0.85) | DGAT1GUSBCHEK2SLC2A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936137-B | Compositions and methods for treating severe constipation | 安济药业公司 | 2023-09-08 | — | — | CN | disclosed |