Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.58 |
| ▸ | CA2 | P00918 | 10/20 | 0.58 |
| ▸ | CA12 | O43570 | 7/20 | 0.58 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | PNMT | P11086 | 7/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366561 | 1.00 | CA1 (0.58) | CA1CA2CA12CA9PNMT | |
| SCHEMBL17825055 | 0.83 | CA12 (0.40) | CA1CA2CA12CA9PNMT | |
| SCHEMBL18022665 | 0.77 | PNMT (0.74) | CA1CA2CA12CA9PNMT | |
| SCHEMBL29710882 | 0.76 | CA1 (0.81) | CA1CA2CA12CA9PNMT | |
| SCHEMBL3238863 | 0.76 | CA1 (0.81) | CA1CA2CA12CA9PNMT | |
| SCHEMBL29290371 | 0.75 | PDE3B (0.56) | CA1CA2CA12CA9PNMT | |
| Hydrochloric Acid SCHEMBL19712095 | 0.75 | PNMT (0.72) | CA1CA2CA12CA9PNMT | |
| SCHEMBL28181041 | 0.75 | PNMT (0.72) | CA1CA2CA12CA9PNMT | |
| SCHEMBL4162141 | 0.73 | CA1 (1.00) | CA1CA2CA12CA9PNMT | |
| SCHEMBL31231831 | 0.73 | CA1 (1.00) | CA1CA2CA12CA9PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023175185-A1 | 2,4-DIOXO-1,4-DIHYDROQUINAZOLINE DERIVATIVES AS PARG INHIBITORS FOR THE TREATMENT OF CANCER | FORX THERAPEUTICS AG (CH) | 2023-09-21 | — | — | WO | disclosed |