SCHEMBL30565985

SCHEMBL30565985

COc1ccnc2[nH]cc(CCN(C)C(C)C)c12

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.45
CCNT1 O60563 5/20 0.43
CDK9 P50750 5/20 0.43
CDK5 Q00535 5/20 0.43
CDK5R1 Q15078 5/20 0.43
CCNA2 P20248 4/20 0.43
CDK2 P24941 4/20 0.43
CCNA1 P78396 4/20 0.43
CYP3A4 P08684 1/20 0.41
HTR1A P08908 1/20 0.41
HTR2A P28223 4/20 0.39
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
AXL P30530 1/20 0.35
LRRK2 Q5S007 1/20 0.34
AURKA O14965 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25286094 1.00 HTR6 (0.45) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL30565937 0.89 CCNT1 (0.44) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL25258956 0.89 CCNT1 (0.44) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL25292886 0.87 HTR6 (0.59) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL30565961 0.87 HTR6 (0.59) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL30565963 0.87 HTR6 (0.59) HTR6CCNT1CDK9CDK5CDK5R1
Hydrochloric Acid SCHEMBL25288264 0.86 HTR6 (0.58) HTR6CCNT1CDK9CDK5CDK5R1
Hydrochloric Acid SCHEMBL31211621 0.86 HTR6 (0.58) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL25987681 0.85 HTR1D (0.38) HTR6CCNT1CDK9CDK5CDK5R1
SCHEMBL25298590 0.85 HTR6 (0.47) HTR6CCNT1CDK9CDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735441-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
WO-2025000051-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2025-01-02 WO disclosed
CN-118974044-A Compounds of formula (I) 赛洛私人有限公司 2024-11-15 CN disclosed
EP-4452979-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 EP disclosed
WO-2023115165-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 WO disclosed