Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 10/20 | 1.00 |
| ▸ | SUV39H1 | O43463 | 3/20 | 0.88 |
| ▸ | PKM | P14618 | 1/20 | 0.88 |
| ▸ | FNTA | P49354 | 1/20 | 0.88 |
| ▸ | FNTB | P49356 | 1/20 | 0.88 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.88 |
| ▸ | RNF31 | Q96EP0 | 1/20 | 0.88 |
| ▸ | RBCK1 | Q9BYM8 | 1/20 | 0.88 |
| ▸ | SHARPIN | Q9H0F6 | 1/20 | 0.88 |
| ▸ | EP300 | Q09472 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gliotoxin SCHEMBL12018743 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL14579856 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL14986985 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL14514067 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL9667270 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL54420 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL12618354 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL13341245 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL4294337 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB | |
| Gliotoxin SCHEMBL12149513 | 0.94 | EHMT2 (1.00) | EHMT2SUV39H1PKMFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11766442-B2 | T-cell lymphoma treatments | CITY OF HOPE (US) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11766442-B2 | T-cell lymphoma treatments | MALT1, BCL6, BCL3 | EHMT2 726/4885SUV39H1 342/4885PKM 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.