Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | MST1R | Q04912 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29267957 | 0.99 | PLK4 (0.43) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL30567530 | 0.79 | PLK4 (0.42) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL30567535 | 0.78 | SCN9A (0.41) | SCN9AQDPRFTOSIGMAR1CCNT1 | |
| SCHEMBL30567526 | 0.78 | SCN9A (0.41) | SCN9AQDPRFTOSIGMAR1CCNT1 | |
| SCHEMBL30853370 | 0.73 | CCNT1 (0.44) | SCN9AQDPRCCNT1CDK9PIK3CD | |
| SCHEMBL27698209 | 0.72 | IKBKB (0.61) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL24597173 | 0.72 | SOS1 (0.45) | ROCK1SCN9AFTOCCNT1CDK9 | |
| SCHEMBL1421939 | 0.70 | BTK (0.58) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL20487617 | 0.68 | BTK (0.57) | PLK4CHEK1AURKADAPK3MAP4K4 | |
| SCHEMBL23185496 | 0.68 | BTK (0.57) | PLK4CHEK1AURKADAPK3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916914-A | SOS1 inhibitors and uses thereof | 锐新医药公司 | 2023-10-20 | — | — | CN | disclosed |