Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | QDPR | P09417 | 3/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567535 | 0.81 | SCN9A (0.41) | SCN9ACCNT1CDK9QDPRFTO | |
| SCHEMBL30567544 | 0.78 | PLK4 (0.44) | SCN9ACCNT1CDK9QDPRFTO | |
| Hydrochloric Acid SCHEMBL29267957 | 0.77 | PLK4 (0.43) | SCN9ACCNT1CDK9QDPRFTO | |
| SCHEMBL30567553 | 0.72 | SCN9A (0.40) | SCN9ACCNT1CDK9QDPRSIGMAR1 | |
| SCHEMBL24597166 | 0.72 | SOS1 (0.45) | CCNT1CDK9FTO | |
| SCHEMBL31484704 | 0.68 | CHEK1 (0.43) | — | |
| SCHEMBL19374274 | 0.67 | QDPR (0.51) | QDPRSIGMAR1HTR2C | |
| SCHEMBL4690601 | 0.67 | IKBKB (0.56) | SIGMAR1HTR2C | |
| SCHEMBL5603681 | 0.67 | QDPR (0.61) | SCN9AQDPRSIGMAR1HTR2C | |
| SCHEMBL16676625 | 0.66 | SCN9A (0.50) | SCN9ACCNT1CDK9FTOSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116916914-A | SOS1 inhibitors and uses thereof | 锐新医药公司 | 2023-10-20 | — | — | CN | disclosed |