Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408573 | 1.00 | CYP11B2 (0.39) | CYP11B2CYP11B1KDM4EALDH1A1BACE1 | |
| SCHEMBL26847559 | 0.84 | PARP10 (0.40) | CYP11B2CYP11B1KDM4EALDH1A1BACE1 | |
| SCHEMBL4681659 | 0.79 | NPY5R (0.46) | KDM4EALDH1A1 | |
| SCHEMBL22633138 | 0.78 | TLR8 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL25407826 | 0.77 | CYP11B2 (0.44) | CYP11B2CYP11B1KDM4EALDH1A1BACE1 | |
| SCHEMBL30567665 | 0.77 | CYP11B2 (0.44) | CYP11B2CYP11B1KDM4EALDH1A1BACE1 | |
| SCHEMBL27762791 | 0.76 | MKNK1 (0.49) | CYP11B2CYP11B1KDM4EALDH1A1TNF | |
| SCHEMBL21744244 | 0.73 | CYP11B2 (0.56) | CYP11B2CYP11B1PARP10PARP11IDH1 | |
| SCHEMBL19406772 | 0.73 | KDM1A (0.44) | CYP11B2CYP11B1BACE1CTSDTNF | |
| SCHEMBL22925944 | 0.72 | PDE2A (0.41) | KDM4EALDH1A1BACE1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615425-A | Compounds and compositions as Sppl2a inhibitors | 诺华股份有限公司 | 2023-08-18 | — | — | CN | disclosed |