Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 10/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410828 | 1.00 | RAB9A (0.41) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL29631171 | 0.84 | KDM4E (0.47) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL20894654 | 0.84 | KDM4E (0.47) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL26847405 | 0.80 | PIK3CD (0.36) | RAB9AGAAPTGESPIK3CDPIK3CA | |
| SCHEMBL29631044 | 0.77 | RAB9A (0.54) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL20894119 | 0.77 | RAB9A (0.54) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL30567657 | 0.76 | RAB9A (0.44) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL25407809 | 0.76 | RAB9A (0.44) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL3745235 | 0.72 | MKNK1 (0.43) | RAB9AKDM4ESMN1; SMN2NPC1POLB | |
| SCHEMBL14141917 | 0.70 | CYP1A2 (0.57) | RAB9AKDM4ESMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116615425-A | Compounds and compositions as Sppl2a inhibitors | 诺华股份有限公司 | 2023-08-18 | — | — | CN | disclosed |