Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 8/20 | 0.65 |
| ▸ | NPY4R | P50391 | 8/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.65 |
| ▸ | NPY1R | P25929 | 6/20 | 0.65 |
| ▸ | KDM1A | O60341 | 3/20 | 0.64 |
| ▸ | VIPR1 | P32241 | 3/20 | 0.60 |
| ▸ | EP300 | Q09472 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | VIPR2 | P41587 | 3/20 | 0.59 |
| ▸ | TFPI | P10646 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843196 | 0.93 | NPY2R (0.63) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL9843188 | 0.93 | NPY2R (0.63) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL29903370 | 0.92 | NPY2R (0.64) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL30338084 | 0.91 | NPY2R (0.62) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL29479811 | 0.91 | NPY2R (0.62) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL30495740 | 0.91 | NPY2R (0.62) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL30607334 | 0.90 | NPY2R (0.68) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL30432021 | 0.90 | NPY2R (0.68) | NPY2RNPY4RNPY5RNPY1REP300 | |
| SCHEMBL31547377 | 0.90 | NPY2R (0.65) | NPY2RNPY4RNPY5RNPY1RKDM1A | |
| SCHEMBL29514978 | 0.90 | KDM1A (0.64) | NPY2RNPY4RNPY5RNPY1RKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-22 | — | — | US | disclosed |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2024-01-25 | — | — | US | disclosed |
| CN-116601290-A | Human chimeric antigen receptor neutrophils, compositions, kits and methods of use | 普渡研究基金会 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885 |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.