SCHEMBL9843196

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.67

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	NPY2R	P49146	8/20	0.63

▸	NPY4R	P50391	8/20	0.63

▸	NPY5R	Q15761	8/20	0.63

▸	NPY1R	P25929	7/20	0.63

▸	MAPK8	P45983	1/20	0.59

▸	MAPK9	P45984	1/20	0.59

▸	MAPK10	P53779	1/20	0.59

▸	KDM1A	O60341	2/20	0.59

▸	EP300	Q09472	1/20	0.57

▸	HIF1A	Q16665	1/20	0.57

▸	NTSR2	O95665	1/20	0.57

▸	NTSR1	P30989	1/20	0.57

▸	SORT1	Q99523	1/20	0.57

▸	TFPI	P10646	2/20	0.56

▸	VIPR2	P41587	2/20	0.56

▸	VIPR1	P32241	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9843188	1.00	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30567697	0.93	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL31547377	0.93	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL29903370	0.91	NPY2R (0.64)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL29416138	0.91	NPY2R (0.65)	NPY2RNPY4RNPY5RNPY1REP300
SCHEMBL31230205	0.91	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL29903364	0.90	NPY2R (0.68)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL30658285	0.90	NPY2R (0.72)	NPY2RNPY4RNPY5RNPY1RMAPK8
SCHEMBL31402802	0.90	NPY2R (0.63)	NPY2RNPY4RNPY5RNPY1RKDM1A
SCHEMBL30338084	0.90	NPY2R (0.62)	NPY2RNPY4RNPY5RNPY1RMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0415470-A2	Aminopeptidase	CAMPINA MELKUNIE B.V. (NL)	1991-03-06	—	—	EP	disclosed