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SCHEMBL30567722

SCHEMBL30567722

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.61
▸ IL23R Q5VWK5 2/20 0.60
▸ VIPR2 P41587 7/20 0.59
▸ VIPR1 P32241 5/20 0.59
▸ GLP1R P43220 2/20 0.58
▸ CCKBR P32239 1/20 0.58
▸ GCGR P47871 1/20 0.57
▸ GIPR P48546 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31498888 0.95 TFPI (0.62) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL29461387 0.92 TFPI (0.63) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL29351238 0.92 TFPI (0.65) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL31683364 0.92 TFPI (0.67) TFPIVIPR2VIPR1
SCHEMBL29794100 0.90 TFPI (0.67) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL31182903 0.89 TFPI (0.65) TFPIVIPR2VIPR1GLP1RCCKBR
SCHEMBL30176471 0.89 VIPR2 (0.63) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL29701273 0.89 TFPI (0.74) TFPIIL23RVIPR2VIPR1GLP1R
SCHEMBL30432173 0.89 VIPR1 (0.69) TFPIVIPR2VIPR1GLP1RCCKBR
SCHEMBL29649202 0.89 IL23R (0.60) TFPIIL23RVIPR2VIPR1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 TFPI 1593/4885IL23R 92/4885VIPR2 2314/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 TFPI 1593/4885IL23R 92/4885VIPR2 2314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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