SCHEMBL29461387

SCHEMBL29461387

CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)C(C)C)[C@@H](C)O

nearest known ligand 0.66

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.63
▸ IL23R Q5VWK5 2/20 0.60
▸ VIPR2 P41587 6/20 0.60
▸ GLP1R P43220 3/20 0.60
▸ GCGR P47871 1/20 0.60
▸ GIPR P48546 1/20 0.60
▸ CCKBR P32239 1/20 0.59
▸ VIPR1 P32241 4/20 0.58
▸ KEAP1 Q14145 1/20 0.58
▸ NR3C1 P04150 2/20 0.57
▸ ECE1 P42892 1/20 0.56
▸ MUS81 Q96NY9 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567722 0.92 TFPI (0.61) TFPIIL23RVIPR2GLP1RGCGR
SCHEMBL29701273 0.91 TFPI (0.74) TFPIIL23RVIPR2GLP1RGCGR
SCHEMBL30431813 0.91 TFPI (0.65) TFPIIL23RVIPR2GLP1RGCGR
SCHEMBL31498888 0.90 TFPI (0.62) TFPIIL23RVIPR2GLP1RGCGR
SCHEMBL30432341 0.90 GLP1R (0.63) TFPIIL23RVIPR2GLP1RGCGR
SCHEMBL29403715 0.90 VIPR1 (0.72) TFPIVIPR2GLP1RGCGRGIPR
SCHEMBL30658586 0.89 TFPI (0.67) TFPIVIPR2GLP1RVIPR1ECE1
SCHEMBL31182935 0.89 TFPI (0.62) TFPIIL23RGLP1RGCGRGIPR
SCHEMBL29387437 0.89 VIPR2 (0.61) TFPIIL23RVIPR2GLP1RCCKBR
SCHEMBL29794100 0.89 TFPI (0.67) TFPIIL23RVIPR2GLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629409-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2026-05-19 — — US disclosed
US-20240226261-A9 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-07-11 — — US disclosed
US-20240131136-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-04-25 — — US disclosed
US-11844828-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-12-19 — — US disclosed
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-08-10 — — US disclosed
US-20230066762-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-03-02 — — US disclosed
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-09-15 — — US disclosed
US-20220152182-A1 VACCINE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-05-19 — — US disclosed
US-11266731-B2 Vaccine GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220288190-A1 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 TFPI 1391/4885IL23R 1762/4885VIPR2 860/4885
US-20230248816-A9 PROCESS FOR PREPARING A COMPOSITION COMPRISING A PROTEIN D POLYPEPTIDE CFD, PEPD, SERPINA6 TFPI 1391/4885IL23R 1762/4885VIPR2 860/4885
US-12629409-B2 Vaccine MRPL21, STT3B, CD47 TFPI 2332/4885IL23R 1123/4885VIPR2 3765/4885
US-20230066762-A1 IMMUNOGENIC COMPOSITION CXCL10, CCL2, CCL11 TFPI 3568/4885IL23R 520/4885VIPR2 1911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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