Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 12/20 | 0.58 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.58 |
| ▸ | CALCR | P30988 | 3/20 | 0.57 |
| ▸ | CCKBR | P32239 | 1/20 | 0.56 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | SCTR | P47872 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567777 | 0.95 | PTH1R (0.61) | GLP1RPTH1RCALCRCRHR1CRHR2 | |
| SCHEMBL30176478 | 0.94 | PTH1R (0.62) | GLP1RPTH1RCALCRCCKBRCRHR1 | |
| SCHEMBL31182663 | 0.93 | CALCR (0.63) | GLP1RPTH1RCALCRCCKBRCRHR1 | |
| SCHEMBL4380506 | 0.93 | GLP1R (0.62) | GLP1RPTH1RCALCRCCKBRCRHR1 | |
| SCHEMBL30567719 | 0.93 | KEAP1 (0.55) | GLP1RCALCRCCKBRCRHR1CRHR2 | |
| SCHEMBL30432505 | 0.92 | GLP1R (0.66) | GLP1RPTH1RCALCRCCKBRCRHR1 | |
| SCHEMBL30435350 | 0.91 | GLP1R (0.62) | GLP1RCALCRCCKBRCRHR1CRHR2 | |
| SCHEMBL31182441 | 0.91 | GLP1R (0.66) | GLP1RCALCRCCKBRCRHR1CRHR2 | |
| SCHEMBL30176464 | 0.90 | PTH1R (0.61) | GLP1RPTH1RCALCRCCKBRCRHR1 | |
| SCHEMBL30495588 | 0.90 | CALCR (0.64) | GLP1RPTH1RCALCRCCKBRCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-22 | — | — | US | disclosed |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2024-01-25 | — | — | US | disclosed |
| CN-116601290-A | Human chimeric antigen receptor neutrophils, compositions, kits and methods of use | 普渡研究基金会 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | GLP1R 2288/4885PTH1R 4342/4885CALCR 889/4885 |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | GLP1R 2288/4885PTH1R 4342/4885CALCR 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.