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SCHEMBL30567727

SCHEMBL30567727

CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NPY2R P49146 7/20 0.61
▸ NPY4R P50391 7/20 0.61
▸ NPY5R Q15761 7/20 0.61
▸ NPY1R P25929 5/20 0.61
▸ TFPI P10646 4/20 0.61
▸ KDM1A O60341 1/20 0.60
▸ MAOB P27338 1/20 0.60
▸ KDM5A P29375 1/20 0.60
▸ KDM1B Q8NB78 1/20 0.60
▸ NMUR2 Q9GZQ4 3/20 0.59
▸ NMUR1 Q9HB89 3/20 0.59
▸ RAMP3 O60896 1/20 0.58
▸ CALCR P30988 1/20 0.58
▸ KEAP1 Q14145 1/20 0.58
▸ CXCR4 P61073 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567770 0.94 CALCR (0.60) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30804665 0.93 TFPI (0.59) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30415378 0.92 TFPI (0.59) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL8067081 0.90 NMUR2 (0.58) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL8067075 0.90 NMUR2 (0.58) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30432104 0.90 TFPI (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29489270 0.90 TFPI (0.58) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL31182963 0.90 TFPI (0.68) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL31182542 0.89 NPY2R (0.69) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29362184 0.89 TFPI (0.66) NPY2RNPY4RNPY5RNPY1RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 NPY2R 3831/4885NPY4R 3873/4885NPY5R 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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