Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 4/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | MC5R | P33032 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | MC1R | Q01726 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 7/20 | 0.57 |
| ▸ | NPY4R | P50391 | 7/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.57 |
| ▸ | NPY1R | P25929 | 5/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.57 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.56 |
| ▸ | NMUR1 | Q9HB89 | 3/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM5A | P29375 | 1/20 | 0.55 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.55 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842174 | 0.91 | MC4R (0.58) | TFPIMC4RMC5RMC3RMC1R | |
| SCHEMBL29489266 | 0.90 | TFPI (0.64) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30415378 | 0.90 | TFPI (0.59) | TFPIMC4RMC5RMC3RMC1R | |
| SCHEMBL30842159 | 0.90 | NMUR2 (0.64) | TFPIMC4RMC5RMC3RMC1R | |
| SCHEMBL30567727 | 0.90 | NPY2R (0.61) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30296665 | 0.89 | NMUR2 (0.51) | CXCR4NMUR2NMUR1RAMP3CALCR | |
| SCHEMBL30495837 | 0.89 | OPRM1 (0.61) | TFPIMC4RMC5RMC3RMC1R | |
| SCHEMBL29410232 | 0.88 | KEAP1 (0.67) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30804665 | 0.87 | TFPI (0.59) | TFPINPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31182744 | 0.87 | NPY2R (0.67) | TFPINPY2RNPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240190952-A1 | IL-18 Binding Protein (IL-18BP) and Antibodies for Treating Inflammatory Diseases | AB2 BIO SA (CH) | 2024-06-13 | — | — | US | disclosed |
| US-11926663-B2 | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases | AB2 BIO SA (CH) | 2024-03-12 | — | — | US | disclosed |
| US-11820817-B2 | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases | AB2 BIO SA (CH) | 2023-11-21 | — | — | US | disclosed |
| US-20230250164-A1 | IL-18 Binding Protein (IL-18BP) In Inflammatory Diseases | AB2 BIO SA (CH) | 2023-08-10 | — | — | US | disclosed |
| US-11530263-B2 | IL-18 binding protein (IL-18BP) in inflammatory diseases | AB2 BIO SA (CH) | 2022-12-20 | — | — | US | disclosed |
| EP-3978526-A1 | IL-18 BINDING PROTEIN (IL-18BP) IN INFLAMMATORY DISEASES | AB2 Bio SA (CH) | 2022-04-06 | — | — | EP | disclosed |