SCHEMBL30567739

SCHEMBL30567739

CSCC[C@H](NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.56
▸ GLP1R P43220 9/20 0.55
▸ SCTR P47872 1/20 0.55
▸ IL23R Q5VWK5 1/20 0.55
▸ APLNR P35414 1/20 0.55
▸ GCGR P47871 1/20 0.52
▸ GIPR P48546 1/20 0.52
▸ PTH1R Q03431 1/20 0.52
▸ MC4R P32245 1/20 0.52
▸ CALCR P30988 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30567761 0.91 GLP1R (0.60) TFPIGLP1RSCTRIL23RGCGR
SCHEMBL30567777 0.91 PTH1R (0.61) GLP1RPTH1RCALCR
SCHEMBL30432835 0.91 IL23R (0.57) GLP1RSCTRIL23RGCGRGIPR
SCHEMBL31182575 0.90 TFPI (0.63) TFPIGLP1RSCTRGCGRGIPR
SCHEMBL30436184 0.89 GLP1R (0.62) TFPIGLP1RSCTRIL23RPTH1R
SCHEMBL30567726 0.89 GLP1R (0.58) GLP1RSCTRPTH1RCALCR
SCHEMBL31307236 0.89 TFPI (0.57) TFPIGLP1RSCTRGCGRGIPR
SCHEMBL30262193 0.89 PTH1R (0.64) GLP1RAPLNRPTH1RCALCR
SCHEMBL30432505 0.88 GLP1R (0.66) GLP1RSCTRPTH1RCALCR
SCHEMBL30432625 0.87 PTH1R (0.59) GLP1RSCTRAPLNRPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 TFPI 1593/4885GLP1R 2288/4885SCTR 228/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 TFPI 1593/4885GLP1R 2288/4885SCTR 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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