Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 7/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | CCKBR | P32239 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | TFPI | P10646 | 1/20 | 0.46 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31452900 | 0.84 | CALCRL (0.54) | APLNRCALCRHCRTR1HCRTR2F2 | |
| SCHEMBL31182546 | 0.83 | APLNR (0.56) | APLNRCALCRMAPK8MAPK9MAPK10 | |
| SCHEMBL30432068 | 0.82 | CALCR (0.66) | APLNRCALCRF2GLP1RKEAP1 | |
| SCHEMBL29856457 | 0.81 | CALCR (0.57) | APLNRCALCRHCRTR1HCRTR2F2 | |
| SCHEMBL30607380 | 0.81 | CALCR (0.63) | CALCRHCRTR1HCRTR2F2CCKBR | |
| SCHEMBL29758433 | 0.81 | F2 (0.56) | CALCRHCRTR1HCRTR2F2RAMP3 | |
| SCHEMBL30997464 | 0.81 | F2 (0.60) | CALCRF2RAMP3 | |
| SCHEMBL31683348 | 0.80 | CALCR (0.69) | CALCRHCRTR1HCRTR2F2CCKBR | |
| SCHEMBL29903283 | 0.80 | CALCR (0.62) | APLNRCALCRHCRTR1HCRTR2F2 | |
| SCHEMBL29400662 | 0.80 | CALCRL (0.58) | CALCRF2CCKBRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-22 | — | — | US | disclosed |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2024-01-25 | — | — | US | disclosed |
| CN-116601290-A | Human chimeric antigen receptor neutrophils, compositions, kits and methods of use | 普渡研究基金会 | 2023-08-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277841-A2 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | APLNR 128/4885CALCR 889/4885HCRTR1 1753/4885 |
| US-20240024473-A1 | HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE | PBK, KIT, MYD88 | APLNR 128/4885CALCR 889/4885HCRTR1 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.