Sugi Predict

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SCHEMBL30567768

SCHEMBL30567768

CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 1/20 0.56
▸ CALCR P30988 1/20 0.56
▸ NMUR2 Q9GZQ4 5/20 0.56
▸ NMUR1 Q9HB89 4/20 0.56
▸ F2 P00734 4/20 0.55
▸ NPY2R P49146 7/20 0.54
▸ NPY4R P50391 7/20 0.54
▸ NPY5R Q15761 7/20 0.54
▸ NPY1R P25929 5/20 0.54
▸ CXCL8 P10145 1/20 0.53
▸ EP300 Q09472 1/20 0.52
▸ HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29681572 0.87 OPRM1 (0.59) NMUR2NMUR1F2CXCL8
SCHEMBL31005066 0.86 TFPI (0.66) CALCRNMUR2NMUR1NPY2RNPY4R
SCHEMBL30567770 0.85 CALCR (0.60) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182741 0.84 CALCR (0.62) RAMP3CALCRNMUR2NMUR1F2
SCHEMBL31332000 0.84 NMUR2 (0.61) NMUR2NMUR1F2NPY2RNPY4R
SCHEMBL31267154 0.84 NMUR2 (0.61) NMUR2NMUR1F2NPY1R
SCHEMBL29746989 0.84 SLC6A2 (0.54) NMUR2F2
SCHEMBL29410248 0.84 NPY2R (0.62) RAMP3CALCRNMUR2NMUR1F2
SCHEMBL30753167 0.83 NMUR2 (0.57) NMUR2NMUR1F2CXCL8
SCHEMBL15094382 0.83 OPRM1 (0.60) NMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 RAMP3 1335/4885CALCR 889/4885NMUR2 810/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 RAMP3 1335/4885CALCR 889/4885NMUR2 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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