Sugi Predict

Sugi Predict / Compounds / SCHEMBL30567778

SCHEMBL30567778

SCHEMBL30567778

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CS)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCCCN)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CALCR P30988 4/20 0.66
▸ HCRTR1 O43613 1/20 0.61
▸ HCRTR2 O43614 1/20 0.61
▸ NPY2R P49146 7/20 0.60
▸ NPY4R P50391 7/20 0.60
▸ NPY5R Q15761 7/20 0.60
▸ NPY1R P25929 5/20 0.60
▸ EP300 Q09472 1/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ OPRM1 P35372 2/20 0.57
▸ OPRD1 P41143 2/20 0.57
▸ OPRK1 P41145 2/20 0.57
▸ CCKBR P32239 2/20 0.57
▸ GLP1R P43220 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30576913 0.93 CALCR (0.65) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL29679500 0.93 CALCR (0.64) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182573 0.92 CALCR (0.66) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL29811064 0.91 CALCR (0.66) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL31182911 0.91 CALCR (0.65) CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL30567772 0.90 CALCR (0.74) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30607403 0.90 CALCR (0.67) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL30958881 0.90 CALCR (0.61) CALCRHCRTR1HCRTR2OPRM1OPRD1
SCHEMBL31182878 0.90 CALCR (0.70) CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL31656508 0.90 CALCR (0.78) CALCRHCRTR1HCRTR2NPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-08-22 — — US disclosed
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PURDUE RESEARCH FOUNDATION (US) 2024-01-25 — — US disclosed
CN-116601290-A Human chimeric antigen receptor neutrophils, compositions, kits and methods of use 普渡研究基金会 2023-08-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277841-A2 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 CALCR 889/4885HCRTR1 1753/4885HCRTR2 3125/4885
US-20240024473-A1 HUMAN CHIMERIC ANTIGEN RECEPTOR NEUTROPHILS, COMPOSITIONS, KITS AND METHODS OF USE PBK, KIT, MYD88 CALCR 889/4885HCRTR1 1753/4885HCRTR2 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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