Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21382148 | 1.00 | CNR1 (0.44) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL21381988 | 0.92 | CNR1 (0.47) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL30567981 | 0.92 | CNR1 (0.47) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL21382052 | 0.85 | KCNH2 (0.46) | CNR1SCN9AKCNH2 | |
| SCHEMBL23211983 | 0.84 | CNR1 (0.46) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL30568014 | 0.84 | CNR1 (0.46) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL22773374 | 0.84 | SCN9A (0.51) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL30568012 | 0.84 | SCN9A (0.57) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL23212070 | 0.84 | SCN9A (0.57) | CNR1SCN9AMEN1KMT2AUSP2 | |
| SCHEMBL23212041 | 0.80 | CNR1 (0.47) | CNR1SCN9AMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |