Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23211983 | 1.00 | CNR1 (0.46) | CNR1CNR2SMN1; SMN2SCN9AUTS2R | |
| SCHEMBL23212041 | 0.93 | CNR1 (0.47) | CNR1CNR2SMN1; SMN2SCN9AUTS2R | |
| SCHEMBL30567980 | 0.93 | CNR1 (0.47) | CNR1CNR2SMN1; SMN2SCN9AUTS2R | |
| SCHEMBL23211952 | 0.86 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL23211915 | 0.85 | CNR1 (0.55) | CNR1SMN1; SMN2SCN9AUTS2RMEN1 | |
| SCHEMBL30568016 | 0.85 | CNR1 (0.55) | CNR1SMN1; SMN2SCN9AUTS2RMEN1 | |
| SCHEMBL21382148 | 0.84 | CNR1 (0.44) | CNR1SMN1; SMN2SCN9AMEN1KMT2A | |
| SCHEMBL30567992 | 0.84 | CNR1 (0.44) | CNR1SMN1; SMN2SCN9AMEN1KMT2A | |
| SCHEMBL23212070 | 0.81 | SCN9A (0.57) | CNR1SMN1; SMN2SCN9AMEN1KMT2A | |
| SCHEMBL30568012 | 0.81 | SCN9A (0.57) | CNR1SMN1; SMN2SCN9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |