Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21427537 | 1.00 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL21427541 | 1.00 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL21427935 | 0.94 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL21408793 | 0.94 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL21408804 | 0.94 | P2RX7 (0.67) | P2RX7 | |
| SCHEMBL21427529 | 0.90 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL21427530 | 0.90 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL21427940 | 0.90 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL21427931 | 0.90 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL30568977 | 0.90 | P2RX7 (0.64) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11919854-B2 | P2RX7 modulators in therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-03-05 | — | — | US | disclosed |
| CN-112512520-B | P2RX7 modulators in therapy | 国家科学研究中心 | 2023-10-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11919854-B2 | P2RX7 modulators in therapy | P2RX7, P2RX2, P2RX1 | P2RX7 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.