Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110937 | 0.68 | — | — | |
| SCHEMBL30910833 | 0.68 | — | — | |
| SCHEMBL8190882 | 0.63 | AKR1B1 (0.38) | AKR1B1 | |
| SCHEMBL14861696 | 0.57 | — | — | |
| SCHEMBL24664708 | 0.55 | — | — | |
| SCHEMBL10583146 | 0.54 | — | — | |
| SCHEMBL8924542 | 0.54 | ALDH1A1 (0.33) | AKR1B1 | |
| SCHEMBL20718281 | 0.54 | — | — | |
| SCHEMBL8645186 | 0.53 | AKR1B1 (0.48) | AKR1B1 | |
| Phenylacetic Acid SCHEMBL9449909 | 0.53 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186069-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-10-05 | — | — | WO | disclosed |