Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513100 | 1.00 | KCNJ1 (0.77) | KCNJ1KCNH2 | |
| SCHEMBL19513099 | 0.87 | KCNJ1 (0.58) | KCNJ1KCNH2 | |
| SCHEMBL30569165 | 0.87 | KCNJ1 (0.58) | KCNJ1KCNH2 | |
| SCHEMBL20945401 | 0.87 | KCNJ1 (0.68) | KCNJ1KCNH2 | |
| SCHEMBL30569155 | 0.87 | KCNJ1 (0.68) | KCNJ1KCNH2 | |
| SCHEMBL16853059 | 0.87 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL31098389 | 0.87 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| SCHEMBL30569153 | 0.87 | KCNJ1 (0.57) | KCNJ1KCNH2 | |
| SCHEMBL20945399 | 0.87 | KCNJ1 (0.57) | KCNJ1KCNH2 | |
| SCHEMBL19475764 | 0.86 | KCNJ1 (0.65) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | disclosed |