Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 19/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19513099 | 1.00 | KCNJ1 (0.58) | KCNJ1KCNH2GRM5 | |
| SCHEMBL19513100 | 0.87 | KCNJ1 (0.77) | KCNJ1KCNH2 | |
| SCHEMBL30569178 | 0.87 | KCNJ1 (0.77) | KCNJ1KCNH2 | |
| SCHEMBL19475679 | 0.86 | KCNJ1 (0.58) | KCNJ1KCNH2 | |
| SCHEMBL20945399 | 0.83 | KCNJ1 (0.57) | KCNJ1KCNH2GRM5 | |
| SCHEMBL30569153 | 0.83 | KCNJ1 (0.57) | KCNJ1KCNH2GRM5 | |
| SCHEMBL30569167 | 0.82 | KCNJ1 (0.65) | KCNJ1KCNH2GRM5 | |
| SCHEMBL20945421 | 0.82 | KCNJ1 (0.65) | KCNJ1KCNH2GRM5 | |
| SCHEMBL20945400 | 0.78 | GRM5 (0.47) | KCNJ1KCNH2GRM5 | |
| SCHEMBL19475753 | 0.77 | KCNJ1 (0.78) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | claimed |
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | disclosed |