Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19475689 | 1.00 | KCNJ1 (0.46) | KCNJ1KCNH2 | |
| SCHEMBL30569166 | 0.85 | MAPT (0.51) | KCNJ1 | |
| SCHEMBL19475649 | 0.85 | MAPT (0.51) | KCNJ1 | |
| SCHEMBL20945405 | 0.79 | KCNJ1 (0.72) | KCNJ1KCNH2 | |
| SCHEMBL26221977 | 0.79 | TP53 (0.35) | KCNJ1 | |
| SCHEMBL19475675 | 0.76 | KCNJ1 (0.51) | KCNJ1KCNH2 | |
| SCHEMBL19475749 | 0.76 | KCNJ1 (0.43) | KCNJ1KCNH2 | |
| SCHEMBL20945398 | 0.75 | KCNJ1 (0.55) | KCNJ1KCNH2 | |
| SCHEMBL30569158 | 0.75 | KCNJ1 (0.55) | KCNJ1KCNH2 | |
| SCHEMBL19475690 | 0.72 | KCNJ1 (0.66) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | disclosed |