Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470970 | 1.00 | PTGS2 (0.63) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL29630290 | 0.88 | PTGS2 (0.62) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL24470975 | 0.88 | PTGS2 (0.62) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604935 | 0.86 | PTGS2 (0.60) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604829 | 0.84 | PTGS2 (0.67) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604805 | 0.84 | PTGS2 (0.58) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18516741 | 0.84 | PTGS2 (0.76) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604966 | 0.83 | PTGS2 (0.57) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL24470667 | 0.83 | MEN1 (0.71) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL29630155 | 0.83 | MEN1 (0.71) | PTGS2ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |