Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | SLC26A4 | O43511 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470689 | 1.00 | CASP3 (0.57) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL30569383 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL30569447 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29104664 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470609 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL26911475 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470692 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470697 | 0.94 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470657 | 0.92 | CASP3 (0.52) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713124 | 0.92 | CASP3 (0.52) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |