Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771271 | 0.78 | AR (0.61) | TNKS2AR | |
| SCHEMBL27977589 | 0.77 | TNKS2 (0.49) | TNKS2CTSVCTSLPGRSMN1; SMN2 | |
| SCHEMBL2798042 | 0.76 | TNKS2 (0.50) | TNKS2ARLMNAMEN1KMT2A | |
| SCHEMBL12075227 | 0.75 | KDM4E (0.57) | TNKS2PDE3BPDE3ALMNAMEN1 | |
| SCHEMBL31441277 | 0.73 | CA12 (0.49) | TNKS2PDE3BPDE3ACTSVCTSL | |
| SCHEMBL20680204 | 0.73 | AR (0.51) | TNKS2ARLMNAMEN1KMT2A | |
| SCHEMBL8210948 | 0.73 | LMNA (0.56) | TNKS2ARLMNAMEN1KMT2A | |
| SCHEMBL20838314 | 0.73 | AR (0.51) | ARLMNAMEN1KMT2ARXFP1 | |
| SCHEMBL1771208 | 0.73 | AR (0.58) | TNKS2ARLMNAMEN1KMT2A | |
| SCHEMBL29722191 | 0.72 | AR (0.58) | ARLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583510-A | (aza) quinolin-4-amine derivatives as P2X3 inhibitors | 奇斯药制品公司 | 2023-08-11 | — | — | CN | disclosed |