SCHEMBL30570974

SCHEMBL30570974

Cc1ccc2c(c1)NCC(C)N2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTR2C P28335 3/20 0.38
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
BRD4 O60885 4/20 0.35
CREBBP Q92793 3/20 0.35
HTR2A P28223 1/20 0.34
HTR2B P41595 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29070709 1.00 CYP1A2 (0.38) CYP1A2CHRNB2CHRNA4NPC1RAB9A
SCHEMBL29070741 0.92 CYP1A2 (0.38) CYP1A2CHRNB2CHRNA4NPC1RAB9A
SCHEMBL30570966 0.92 CYP1A2 (0.38) CYP1A2CHRNB2CHRNA4NPC1RAB9A
SCHEMBL16722790 0.79 BRD4 (0.33) BRD4CREBBPEP300
SCHEMBL29004245 0.79 HTR2C (0.40) CYP1A2CHRNB2CHRNA4NPC1RAB9A
SCHEMBL24290488 0.79 PNMT (0.42) NPC1RAB9AHTR2CBRD4HTR2A
SCHEMBL29070708 0.79 HTR2C (0.40) CHRNB2CHRNA4HTR2CBRD4CREBBP
SCHEMBL16722791 0.79 PNMT (0.42) NPC1RAB9AHTR2CBRD4HTR2A
SCHEMBL15508323 0.79 HTR2C (0.40) CYP1A2CHRNB2CHRNA4NPC1RAB9A
SCHEMBL29004248 0.79 HTR2C (0.40) CYP1A2CHRNB2CHRNA4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116751170-A Method for directly preparing semi-hydrogenated nitrogen-containing aromatic heterocyclic compound from sugar 浙江大学 2023-09-15 CN disclosed