Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718605 | 1.00 | NOTUM (0.53) | NOTUMTP53PDE4APDE4BPDE4C | |
| SCHEMBL29187823 | 0.73 | NOTUM (0.47) | NOTUMTP53PDE4APDE4BPDE4C | |
| SCHEMBL7270589 | 0.72 | CA12 (0.50) | POLBLMNACA12CA1CA2 | |
| SCHEMBL22102561 | 0.72 | CA12 (0.50) | LMNACA12CA1CA2CA7 | |
| SCHEMBL29660431 | 0.72 | CA12 (0.50) | LMNACA12CA1CA2CA7 | |
| SCHEMBL29631031 | 0.70 | NOTUM (0.62) | NOTUMTP53LMNASMN1; SMN2KDM4E | |
| SCHEMBL20894496 | 0.70 | NOTUM (0.62) | NOTUMTP53LMNASMN1; SMN2KDM4E | |
| SCHEMBL3895361 | 0.70 | NOTUM (1.00) | NOTUM | |
| SCHEMBL30730960 | 0.70 | NOTUM (1.00) | NOTUM | |
| SCHEMBL22312090 | 0.69 | NOTUM (0.84) | NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116602950-A | Methods of treating fibrosis | 诺格拉制药有限公司 | 2023-08-18 | — | — | CN | disclosed |