Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30573244 | 1.00 | NOTUM (0.53) | NOTUMTP53PDE4APDE4BPDE4C | |
| SCHEMBL29187823 | 0.73 | NOTUM (0.47) | NOTUMTP53PDE4APDE4BPDE4C | |
| SCHEMBL7270589 | 0.72 | CA12 (0.50) | POLBLMNACA12CA1CA2 | |
| SCHEMBL22102561 | 0.72 | CA12 (0.50) | LMNACA12CA1CA2CA7 | |
| SCHEMBL29660431 | 0.72 | CA12 (0.50) | LMNACA12CA1CA2CA7 | |
| SCHEMBL29631031 | 0.70 | NOTUM (0.62) | NOTUMTP53LMNASMN1; SMN2KDM4E | |
| SCHEMBL20894496 | 0.70 | NOTUM (0.62) | NOTUMTP53LMNASMN1; SMN2KDM4E | |
| SCHEMBL3895361 | 0.70 | NOTUM (1.00) | NOTUM | |
| SCHEMBL30730960 | 0.70 | NOTUM (1.00) | NOTUM | |
| SCHEMBL22312090 | 0.69 | NOTUM (0.84) | NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115159-A1 | ALKYLAMIDO COMPOUNDS AND USES THEREOF | NOGRA PHARMA LTD (IE) | 2026-04-30 | — | — | US | disclosed |
| US-12291494-B2 | Methods of treating fibrosis | NOGRA PHARMA LIMITED (IE) | 2025-05-06 | — | — | US | disclosed |
| US-20240279157-A1 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LIMITED (IE) | 2024-08-22 | — | — | US | disclosed |
| US-11753365-B2 | Methods of treating fibrosis | NOGRA PHARMA LIMITED (IE) | 2023-09-12 | — | — | US | disclosed |
| CN-116602950-A | Methods of treating fibrosis | 诺格拉制药有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-20220354809-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2022-11-10 | — | — | US | disclosed |
| US-20220033346-A1 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LIMITED (IE) | 2022-02-03 | — | — | US | disclosed |
| US-11046641-B2 | Methods of treating fibrosis | NOGRA PHARMA LIMITED (IE) | 2021-06-29 | — | — | US | disclosed |
| US-20210113505-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | NOGRA PHARMA LTD (IE) | 2021-04-22 | — | — | US | disclosed |
| US-10959970-B2 | Methods of treating hair related conditions | NOGRA PHARMA LIMITED (IE) | 2021-03-30 | — | — | US | disclosed |
| WO-2014041140-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | NOGRA PHARMA LIMITED (IE) | 2014-03-20 | — | — | WO | disclosed |
| WO-2013156413-A1 | METHODS OF TREATING LACTOSE INTOLERANCE | NOGRA PHARMA LIMITED (IE) | 2013-10-24 | — | — | WO | disclosed |
| WO-2013117744-A9 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LIMITED (IE) | 2013-10-03 | — | — | WO | disclosed |
| WO-2013117744-A2 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LIMITED (IE) | 2013-08-15 | — | — | WO | disclosed |
| US-20120053245-A1 | Methods of Treating Hair Related Conditions | GIULIANI INTERNATIONAL, LTD. (IE) | 2012-03-01 | — | — | US | disclosed |
| US-20120053244-A1 | Alkylamido Compounds and Uses Thereof | NOGRA PHARMA LIMITED (IE) | 2012-03-01 | — | — | US | disclosed |
| EP-2396082-A2 | METHODS FOR TREATING HAIR RELATED CONDITIONS | Giuliani International Limited (IE) | 2011-12-21 | — | — | EP | disclosed |
| EP-2396081-A2 | ALKYLAMIDO COMPOUNDS AND USES THEREOF | Giuliani International Limited (IE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091894-A2 | METHODS OF TREATING HAIR RELATED CONDITIONS | GIULIANI INTERNATIONAL LIMITED (IE) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010091892-A2 | ALKYLAMIDO COMPOUNDS AND USES THEREOF | GIULIANI INTERNATIONAL LIMITED (IE) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220354809-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | NOTUM 2841/4885TP53 338/4885PDE4A 1122/4885 |
| US-11753365-B2 | Methods of treating fibrosis | MMP1, MMP8, FABP2 | NOTUM 2067/4885TP53 3711/4885PDE4A 898/4885 |
| US-20120053245-A1 | Methods of Treating Hair Related Conditions | PPARA, PPARG, PPARD | NOTUM 1558/4885TP53 4071/4885PDE4A 148/4885 |
| US-20210113505-A1 | METHODS OF TREATING HAIR RELATED CONDITIONS | EBP, AADAT, ALDH7A1 | NOTUM 1432/4885TP53 2494/4885PDE4A 821/4885 |
| US-20240279157-A1 | METHODS OF TREATING FIBROSIS | MMP1, MMP8, FABP2 | NOTUM 2067/4885TP53 3711/4885PDE4A 898/4885 |
| US-20260115159-A1 | ALKYLAMIDO COMPOUNDS AND USES THEREOF | EGFR, PPARD, PPARG | NOTUM 509/4885TP53 2370/4885PDE4A 1138/4885 |
| US-10959970-B2 | Methods of treating hair related conditions | PPARA, PPARG, PPARD | NOTUM 1558/4885TP53 4071/4885PDE4A 148/4885 |
| US-20120053244-A1 | Alkylamido Compounds and Uses Thereof | EGFR, PPARG, ERBB3 | NOTUM 2841/4885TP53 338/4885PDE4A 1122/4885 |
| US-12291494-B2 | Methods of treating fibrosis | MMP1, MMP8, FABP2 | NOTUM 2067/4885TP53 3711/4885PDE4A 898/4885 |
| US-11046641-B2 | Methods of treating fibrosis | MMP1, MMP8, FABP2 | NOTUM 2067/4885TP53 3711/4885PDE4A 898/4885 |
| US-20220033346-A1 | METHODS OF TREATING FIBROSIS | MMP1, MMP8, FABP2 | NOTUM 2067/4885TP53 3711/4885PDE4A 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.