Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP36 | Q9P275 | 10/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737572 | 0.81 | MEN1 (0.68) | USP36MEN1KMT2ANPC1RAB9A | |
| SCHEMBL792186 | 0.81 | MEN1 (0.68) | USP36MEN1KMT2ANPC1RAB9A | |
| SCHEMBL14992382 | 0.79 | HTT (0.73) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30739967 | 0.79 | LMNA (0.78) | MEN1KMT2ANPC1RAB9AKCNQ3 | |
| SCHEMBL1409100 | 0.79 | BRAF (0.55) | USP36ABL1 | |
| SCHEMBL29921719 | 0.78 | BRAF (0.54) | USP36ABL1 | |
| SCHEMBL29071356 | 0.78 | BRAF (0.54) | USP36ABL1 | |
| SCHEMBL24118075 | 0.77 | USP36 (0.45) | USP36ABL1 | |
| SCHEMBL21504265 | 0.77 | IDO1 (0.64) | USP36 | |
| SCHEMBL24600061 | 0.77 | USP36 (1.00) | USP36 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466929-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS | MILLENNIUM PHARM INC (US) | 2023-09-06 | — | — | EP | disclosed |