SCHEMBL305741

SCHEMBL305741

Cc1cc(Br)c(Nc2ccc(O)c3c2C(=O)c2ccccc2C3=O)c(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 8/20 0.52
▸ MEN1 O00255 8/20 0.52
▸ KMT2A Q03164 8/20 0.52
▸ TDP1 Q9NUW8 6/20 0.52
▸ MAPK1 P28482 5/20 0.52
▸ L3MBTL1 Q9Y468 4/20 0.52
▸ NPSR1 Q6W5P4 3/20 0.52
▸ NPC1 O15118 2/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ MAOA P21397 2/20 0.50
▸ PRKCA P17252 2/20 0.47
▸ POLB P06746 4/20 0.43
▸ HPGD P15428 4/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ PABPC1 P11940 1/20 0.43
▸ CSNK1A1 P48729 1/20 0.43
▸ CSNK1D P48730 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ MCL1 Q07820 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978443 0.92 MAPT (0.48) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL31150724 0.92 MAPT (0.48) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL13893505 0.89 MEN1 (0.47) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL16985236 0.86 MAPT (0.56) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL30900833 0.85 MAPT (0.54) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL6152379 0.85 MAPT (0.54) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL5187217 0.85 MAPT (0.59) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL12798083 0.83 MEN1 (0.52) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL6546536 0.82 MAPT (0.54) MAPTMEN1KMT2ATDP1MAPK1
SCHEMBL13884856 0.81 MAPT (0.53) MAPTMEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8092963-B2 Toner compositions XEROX CORPORATION (US) 2012-01-10 — — US claimed
US-4643537-A POLYOL(ALLYL CARBONATE WITH 1-(2,6-DIBROMO-4-METHYLPHENYL) AMINO)-4-HYDROXY-9,10-ANTHRACENEDIONE PPG INDUSTRIES, INC. (US) 1987-02-17 — — US claimed
US-10065210-B2 Breach or contamination indicating article, optionally with pre-warning indicator Ansell Limited (AU) 2018-09-04 — — US disclosed
US-9579532-B2 Breach or contamination indicating article Ansell Limited (AU) 2017-02-28 — — US disclosed
EP-2969566-A1 BREACH OR CONTAMINATION INDICATING ARTICLE Ansell Limited (AU) 2016-01-20 — — EP disclosed
US-20150362435-A1 BREACH OR CONTAMINATION INDICATING ARTICLE, OPTIONALLY WITH PRE-WARNING INDICATOR Ansell Limited (AU) 2015-12-17 — — US disclosed
WO-2015188221-A1 BREACH OR CONTAMINATION INDICATING ARTICLE, OPTIONALLY WITH PRE-WARNING INDICATOR Ansell Limited (AU) 2015-12-17 — — WO disclosed
WO-2014138782-A1 BREACH OR CONTAMINATION INDICATING ARTICLE Ansell Limited (AU) 2014-09-18 — — WO disclosed
US-20140259332-A1 BREACH OR CONTAMINATION INDICATING ARTICLE Ansell Limited (AU) 2014-09-18 — — US disclosed
US-8262790-B2 Colored particles CANON KABUSHIKI KAISHA (JP) 2012-09-11 — — US disclosed
US-8262790-B2 Colored particles CANON KABUSHIKI KAISHA (JP) 2012-09-11 — — US disclosed
US-20110023749-A1 COLORED PARTICLES CANON KABUSHIKI KAISHA (JP) 2011-02-03 — — US disclosed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 — — US disclosed
US-7524979-B2 Methods of making colorant compounds XEROX CORPORATION (US) 2009-04-28 — — US disclosed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 — — US disclosed
US-7301025-B2 N-(2-(2-(alkyl[carbamoyl, carbonyloxy or ureido]alkyl)pyridinium)-5-(carboxy or sulfo)phenyl-8-((2-(N-alkyl[carbamoyl or ureido]alkyl)pyridinyl) xanthene ligands complexed with a metal or metal-containing moiety; magenta dye with improved heat resistance; hot melts or phase change inks XEROX CORPORATION (US) 2007-11-27 — — US disclosed
US-7176317-B2 Colorant compounds XEROX CORPORATION (US) 2007-02-13 — — US disclosed
US-5369141-A Opthalmic lenses PPG INDUSTRIES, INC. (US) 1994-11-29 — — US disclosed
US-4643537-A POLYOL(ALLYL CARBONATE WITH 1-(2,6-DIBROMO-4-METHYLPHENYL) AMINO)-4-HYDROXY-9,10-ANTHRACENEDIONE PPG INDUSTRIES, INC. (US) 1987-02-17 — — US disclosed
US-4643537-A POLYOL(ALLYL CARBONATE WITH 1-(2,6-DIBROMO-4-METHYLPHENYL) AMINO)-4-HYDROXY-9,10-ANTHRACENEDIONE PPG INDUSTRIES, INC. (US) 1987-02-17 — — US disclosed
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