SCHEMBL6152379

SCHEMBL6152379

Cc1cc(C)c(Nc2ccc(Nc3c(C)cc(C)cc3Br)c3c2C(=O)c2ccccc2C3=O)c(Br)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.54
▸ MEN1 O00255 5/20 0.54
▸ KMT2A Q03164 5/20 0.54
▸ TDP1 Q9NUW8 4/20 0.54
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ MAPK1 P28482 3/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ NSD2 O96028 2/20 0.54
▸ POLB P06746 2/20 0.54
▸ THRB P10828 2/20 0.54
▸ HPGD P15428 2/20 0.54
▸ RECQL P46063 2/20 0.54
▸ P2RY1 P47900 2/20 0.54
▸ NPSR1 Q6W5P4 2/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.54
▸ RAB9A P51151 2/20 0.44
▸ P2RY4 P51582 4/20 0.44
▸ P2RY2 P41231 3/20 0.44
▸ RAPGEF4 Q8WZA2 2/20 0.42
▸ HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30900833 1.00 MAPT (0.54) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL9978443 0.93 MAPT (0.48) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL31150724 0.93 MAPT (0.48) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL28561219 0.91 MAPT (0.50) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL29369318 0.90 MAPT (0.64) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL1047268 0.90 MAPT (0.64) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL305741 0.85 MAPT (0.52) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL18294468 0.84 MAPT (0.51) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL6546536 0.83 MAPT (0.54) MAPTMEN1KMT2ATDP1SMN1; SMN2
SCHEMBL20520388 0.83 RAPGEF4 (0.63) MAPTMEN1KMT2ATDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11583373-B2 Coloured curable composition for additive manufacturing processes, 3-dim composite article and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-21 — — US disclosed
EP-3504017-B1 COLOURED CURABLE COMPOSITION FOR ADDITIVE MANUFACTURING PROCESSES, 3-DIM COMPOSITE ARTICLE AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2022-03-30 — — EP disclosed
US-10688522-B2 Method of coating a lens and lens support TRANSITIONS OPTICAL, INC. (US) 2020-06-23 — — US disclosed
US-10619098-B2 Ultraviolet light absorbers TRANSITIONS OPTICAL, INC. (US) 2020-04-14 — — US disclosed
US-10444537-B2 Optical article having a photoluminescent mark TRANSITIONS OPTICAL, INC. (US) 2019-10-15 — — US disclosed
US-20190201171-A1 COLOURED CURABLE COMPOSITION FOR ADDITIVE MANUFACTURING PROCESSES, 3-dim COMPOSITE ARTICLE AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2019-07-04 — — US disclosed
EP-3504017-A1 COLOURED CURABLE COMPOSITION FOR ADDITIVE MANUFACTURING PROCESSES, 3-DIM COMPOSITE ARTICLE AND USE THEREOF 3M Innovative Properties Company (US) 2019-07-03 — — EP disclosed
US-10281628-B2 Method of preparing a photochromic optical article using an organic solvent pretreatment and photochromic coating TRANSITIONS OPTICAL, INC. (US) 2019-05-07 — — US disclosed
EP-3248054-B1 OPTICAL ARTICLE HAVING A PHOTOLUMINESCENT MARK TRANSITIONS OPTICAL INC (US) 2018-12-12 — — EP disclosed
EP-3201292-B1 ULTRAVIOLET LIGHT ABSORBERS TRANSITIONS OPTICAL INC (US) 2018-08-01 — — EP disclosed
EP-1196466-A1 POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) PPG Industries Ohio, Inc. (US) 2002-04-17 — — EP disclosed
US-6316570-B1 FOR PRODUCING POLYMERIZATES HAVING CLARITY, GOOD FLEXIBILITY, ABRASION RESISTANCE WHICH ARE USED IN PREPARATION OF MOLDED ARTICLES SUCH AS LENSES PPG INDUSTRIES OHIO, INC. 2001-11-13 — — US disclosed
WO-2000078832-A1 POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) PPG INDUSTRIES OHIO, INC. (US) 2000-12-28 — — WO disclosed
US-6051360-A A REACTION PRODUCT OF A CHROMOPHORIC NUCLEUS AND A BISPHENOL; EXCELLENT SOLUBILITY IN SOLVENTS AND BINDER RESINS; COLOR FILTERS FOR DISPLAY DEVICES SUCH AS LIQUID CRYSTAL TELEVISION AND COLOR SEPARATION FILTERS FOR IMAGE PICKUP TUBES MITSUI CHEMICALS, INC. (JP) 2000-04-18 — — US disclosed
EP-0633296-B1 Novel dyestuffs and their use MITSUI CHEMICALS INC (JP) 1999-10-13 — — EP disclosed
US-5773172-A SOLVENT AND BINDER SOLUBILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1998-06-30 — — US disclosed
EP-0564237-B1 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS (JP) 1998-03-11 — — EP disclosed
US-5482804-A Resin composition for color filter MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-01-09 — — US disclosed
EP-0633296-A1 Novel dyestuffs and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-01-11 — — EP disclosed
EP-0564237-A2 Preparation of color filter and photo-setting resin therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-10-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10619098-B2 Ultraviolet light absorbers ERCC1, MCM4, ERCC4 MAPT 80/4885MEN1 36/4885KMT2A 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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