Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 1.00 |
| ▸ | PDCD1 | Q15116 | 16/20 | 1.00 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849668 | 1.00 | CD274 (1.00) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL22132095 | 0.96 | CD274 (0.93) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20763763 | 0.96 | CD274 (0.93) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20763538 | 0.95 | CD274 (0.90) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20763783 | 0.94 | CD274 (0.89) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL16566296 | 0.93 | CD274 (1.00) | CD274PDCD1 | |
| SCHEMBL29382060 | 0.93 | CD274 (1.00) | CD274PDCD1 | |
| Hydrochloric Acid SCHEMBL19100243 | 0.93 | CD274 (1.00) | CD274PDCD1 | |
| SCHEMBL20763747 | 0.92 | CD274 (0.85) | CD274PDCD1 | |
| SCHEMBL20763789 | 0.92 | CD274 (0.85) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4493695-A2 | COMBINATION OF STAT3 TARGETING OLIGONUCLEOTIDES AND PD-L1 INHIBITORS | Dicerna Pharmaceuticals, Inc. (US) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023178141-A2 | COMBINATION OF STAT3 TARGETING OLIGONUCLEOTIDES AND PD-L1 INHIBITORS | DICERNA PHARMACEUTICALS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |