SCHEMBL30574346

SCHEMBL30574346

FC(F)c1nnc(-c2ccc(COc3nccn4ccnc34)nc2)o1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 16/20 0.48
HDAC1 Q13547 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26121631 1.00 HDAC6 (0.48) HDAC6HDAC1
SCHEMBL26530754 0.92 HDAC6 (0.42) HDAC6HDAC1
SCHEMBL26529961 0.87 HDAC6 (0.52) HDAC6HDAC1
SCHEMBL26125149 0.82 HDAC6 (0.52) HDAC6HDAC1
SCHEMBL31336066 0.82 HDAC6 (0.52) HDAC6HDAC1
SCHEMBL26530026 0.81 HDAC6 (0.54) HDAC6HDAC1
SCHEMBL30574372 0.81 HDAC6 (0.51) HDAC6HDAC1
SCHEMBL26121601 0.81 HDAC6 (0.51) HDAC6HDAC1
SCHEMBL26529941 0.80 HDAC6 (0.50) HDAC6HDAC1
SCHEMBL26529949 0.78 HDAC6 (0.55) HDAC6HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504190-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF Eikonizo Therapeutics, Inc. (US) 2025-02-12 EP disclosed
CN-119212707-A Oxadiazole HDAC6 inhibitors and uses thereof 艾科尼佐治疗股份有限公司 2024-12-27 CN disclosed
WO-2023196601-A1 OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF EIKONIZO THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed