Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7 | P36402 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361082 | 1.00 | USP7 (0.48) | USP7SYKTRPA1HTR2AHTR2C | |
| SCHEMBL21412250 | 0.85 | USP7 (0.56) | USP7TRPA1ARAPPCCNC | |
| SCHEMBL31754002 | 0.84 | HTR2A (0.62) | USP7HTR2AHTR2CHTR2BPDE1C | |
| SCHEMBL15730607 | 0.84 | HTR2A (0.62) | USP7HTR2AHTR2CHTR2BPDE1C | |
| SCHEMBL15152227 | 0.81 | CDC7 (0.56) | USP7SYKMAOBMAOAACHE | |
| SCHEMBL424964 | 0.78 | TRPA1 (0.46) | TRPA1MAOBMAOAACHECTNNB1 | |
| SCHEMBL28181236 | 0.78 | HTR2A (0.46) | HTR2AHTR2CHTR2BCTNNB1ALDH1A1 | |
| SCHEMBL29769166 | 0.78 | TRPA1 (0.46) | TRPA1MAOBMAOAACHECTNNB1 | |
| SCHEMBL31558323 | 0.77 | CYSLTR2 (0.45) | USP7SYKMAOBNPC1ALDH1A1 | |
| SCHEMBL2118942 | 0.76 | MAOB (0.46) | TRPA1MAOBMAOAACHECTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504190-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | Eikonizo Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2025011623-A1 | CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |
| WO-2023196601-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |