SCHEMBL30574643

SCHEMBL30574643

CC1(C)CN(c2ccn3ncc(C(N)=O)c3n2)CCO1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 5/20 0.50
NTRK1 P04629 11/20 0.46
JAK2 O60674 10/20 0.46
SMPD3 Q9NY59 3/20 0.46
PRKDC P78527 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21997238 0.91 PRKDC (0.45) IRAK4SMPD3PRKDC
SCHEMBL26765837 0.91 PRKDC (0.45) IRAK4SMPD3PRKDC
SCHEMBL29767983 0.87 IRAK4 (0.48) IRAK4NTRK1JAK2SMPD3
SCHEMBL21997182 0.85 IRAK4 (0.41) IRAK4SMPD3PRKDC
SCHEMBL29768077 0.83 NTRK1 (0.49) IRAK4NTRK1JAK2SMPD3
SCHEMBL29692535 0.83 SMPD3 (0.66) IRAK4NTRK1JAK2SMPD3
Hydrochloric Acid SCHEMBL30460079 0.82 SMPD3 (0.64) IRAK4NTRK1JAK2SMPD3
SCHEMBL25970271 0.80 SMPD3 (0.45) IRAK4SMPD3PRKDC
SCHEMBL26765506 0.79 IRAK4 (0.44) IRAK4SMPD3
SCHEMBL26765718 0.79 IRAK4 (0.44) IRAK4SMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116648248-B Aromatic compound, pharmaceutical composition containing same and application thereof 成都茵创园医药科技有限公司 2025-04-15 CN disclosed
CN-116648248-A Aromatic compound, pharmaceutical composition containing same and application thereof 成都茵创园医药科技有限公司 2023-08-25 CN disclosed