Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575762 | 0.89 | CHEK1 (0.50) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL8823285 | 0.84 | CNR2 (0.48) | CNR2LIPGTDP1L3MBTL1MAPT | |
| SCHEMBL30537734 | 0.84 | CNR2 (0.48) | CNR2LIPGTDP1L3MBTL1MAPT | |
| SCHEMBL3677393 | 0.82 | LIPG (0.53) | CNR2LIPGHTTTDP1MAPT | |
| SCHEMBL11893013 | 0.81 | CHEK1 (0.53) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL30537736 | 0.81 | LIPG (0.57) | CNR2LIPGHTTTDP1MAPT | |
| SCHEMBL11779245 | 0.81 | LIPG (0.57) | CNR2LIPGHTTTDP1MAPT | |
| SCHEMBL22080283 | 0.78 | CYP1A2 (0.46) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL19248497 | 0.78 | TLR8 (0.50) | CNR2LIPG | |
| SCHEMBL29763684 | 0.78 | PTPN1 (0.37) | CNR2KEAP1NFE2L2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836062-B | Preparation method of N, N-dimethyl-1-naphthylamine compound | 大连理工大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-116836062-A | Efficient preparation method of N, N-dimethyl-1-naphthylamine compound | 大连理工大学 | 2023-10-03 | — | — | CN | disclosed |