⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247768 | 0.70 | — | — | |
| SCHEMBL4068982 | 0.65 | — | — | |
| SCHEMBL973964 | 0.62 | — | — | |
| SCHEMBL10403807 | 0.61 | ALDH1A1 (0.30) | — | |
| SCHEMBL8145093 | 0.61 | DYRK1A (0.34) | — | |
| SCHEMBL8645913 | 0.60 | — | — | |
| SCHEMBL858847 | 0.60 | — | — | |
| SCHEMBL130376 | 0.59 | — | — | |
| SCHEMBL14306269 | 0.58 | MKNK1 (0.38) | — | |
| SCHEMBL9935156 | 0.58 | MKNK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | claimed |
| EP-3847159-A2 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | Magenta Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | claimed |
| EP-1200398-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2002-05-02 | — | — | EP | claimed |
| WO-2001005756-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN SPA (IT) | 2001-01-25 | — | — | WO | claimed |
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |
| EP-0845026-A1 | MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES | CALL, Hans-Peter Dr. (DE) | 1998-06-03 | — | — | EP | claimed |
| WO-1997048786-A1 | MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES | CALL HANS PETER (DE) | 1997-12-24 | — | — | WO | claimed |
| EP-0717143-A1 | Multicomponents system for modifying decomposing or bleaching of lignin or materials containing it or similar components and the way to use it | Lignozym GmbH (DE) | 1996-06-19 | — | — | EP | claimed |
| US-5089489-A | Enzyme inhibitors | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-02-18 | — | — | US | claimed |
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | claimed |
| EP-0053961-B1 | THIOVINYL-3-CEPHALOSPORIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1984-10-24 | — | — | EP | claimed |
| CN-119233820-A | Azo compounds for the treatment of fibrotic diseases | 乔治-奥古斯特-哥廷根公法基金会大学的大学医学院 | 2024-12-31 | — | — | CN | disclosed |
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | GENETIC INTELLIGENCE INC (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167447-A1 | Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof | GENETIC INTELLIGENCE INC (US) | 2023-06-01 | — | — | US | disclosed |
| US-20220067249-A1 | Machine Learning to Accelerate Design of Energetic Materials | IMAGARS LLC (US) | 2022-03-03 | — | — | US | disclosed |
| US-4413055-A | Silver halide emulsion, a photographic material and a process for the production of photographic images | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-11-01 | — | — | US | disclosed |
| US-4401751-A | REDUCING FOG, INCREASING SHUTTER SPEED, POLYMER WITH 8-HYDROXYQUINOLIN UNITS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |
| US-4366231-A | Photographic material containing a stabilizer, a process for its production, a development process, new pyrazoles, a process for their production and intermediate products | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1982-12-28 | — | — | US | disclosed |
| US-4307186-A | IMPROVED ANTIFOGGING AND FLATTENING OF SILVER HALIDE EMULSION WITH TETRAAZAINDENES PENTAAZAINDENES OR TRIAZAINDOLIZINES | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |
| US-4021248-A | SILVER HALIDE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |