Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 5/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 2/20 | 0.31 |
| ▸ | CHUK | O15111 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540594 | 0.89 | CD38 (0.36) | CD38 | |
| SCHEMBL30577575 | 0.87 | CD38 (0.35) | CD38MAPK1 | |
| SCHEMBL30540566 | 0.85 | CD38 (0.35) | CD38 | |
| SCHEMBL30540620 | 0.76 | LRRK2 (0.33) | CD38GRM2 | |
| SCHEMBL30521273 | 0.76 | KHK (0.35) | CD38 | |
| SCHEMBL30540658 | 0.76 | CD38 (0.35) | CD38GRM2 | |
| SCHEMBL30540469 | 0.75 | KAT2B (0.35) | CD38 | |
| SCHEMBL30540507 | 0.75 | P2RX7 (0.34) | CD38GRM2 | |
| SCHEMBL30577625 | 0.75 | P2RX7 (0.34) | CD38GRM2 | |
| SCHEMBL30577542 | 0.75 | P2RX7 (0.34) | CD38GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151641-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BEIGENE , LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |