SCHEMBL30577620

SCHEMBL30577620

CC(O)c1cc(C#N)nc2ccn(COCC[Si](C)(C)C)c12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30540669 0.83 DGAT1 (0.31) DGAT1
SCHEMBL30577608 0.82 DGAT1 (0.32) DGAT1
SCHEMBL30540436 0.82 DGAT1 (0.32) DGAT1
SCHEMBL30577646 0.81 KLKB1 (0.35) DGAT1
SCHEMBL30577668 0.81 DGAT1 (0.31) DGAT1
SCHEMBL30540664 0.80 DGAT1 (0.30) DGAT1
SCHEMBL30577670 0.79 HRH2 (0.33)
SCHEMBL2428714 0.73 DGAT1 (0.39) DGAT1
SCHEMBL12904174 0.73 DGAT1 (0.37) DGAT1
SCHEMBL31578339 0.71 IDH1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023151641-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH BEIGENE , LTD. (KY) 2023-08-17 WO disclosed