Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336522 | 0.81 | USP2 (0.38) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29366691 | 0.81 | USP2 (0.38) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL20337484 | 0.79 | USP2 (0.37) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL29959213 | 0.79 | USP2 (0.37) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL31184416 | 0.79 | USP2 (0.37) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL18320481 | 0.79 | USP2 (0.37) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL16914260 | 0.79 | USP30 (0.43) | USP30USP2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL18320482 | 0.77 | ESR2 (0.34) | USP30USP2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL31566827 | 0.77 | USP30 (0.41) | USP30USP2SMN1; SMN2TSHRALOX15 | |
| SCHEMBL19641205 | 0.77 | USP2 (0.37) | USP30USP2SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731044-A | Pyrimidine-containing polycyclic biological inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-09-12 | — | — | CN | disclosed |