Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370757 | 1.00 | CYP2D6 (0.72) | CYP2D6CYP2C9HIF1APRMT6OPRK1 | |
| SCHEMBL1397213 | 0.98 | CYP2D6 (0.75) | CYP2D6CYP2C9HIF1APRMT6OPRK1 | |
| SCHEMBL7692768 | 0.97 | CYP2D6 (0.68) | CYP2D6CYP2C9HIF1APRMT6OPRK1 | |
| SCHEMBL4164833 | 0.86 | NCF1 (0.61) | CYP2D6CYP2C9HIF1AOPRK1SMN1; SMN2 | |
| SCHEMBL4176561 | 0.86 | SLC6A4 (0.58) | CYP2D6CYP2C9HIF1AOPRK1 | |
| SCHEMBL30799020 | 0.86 | SLC6A4 (0.58) | CYP2D6CYP2C9HIF1AOPRK1 | |
| SCHEMBL6072051 | 0.86 | HDAC6 (0.57) | CYP2D6CYP2C9HIF1AOPRK1SMN1; SMN2 | |
| SCHEMBL29864585 | 0.86 | NCF1 (0.61) | CYP2D6CYP2C9HIF1AOPRK1SMN1; SMN2 | |
| SCHEMBL30577945 | 0.86 | MEN1 (0.57) | CYP2D6CYP2C9HIF1AOPRK1SMN1; SMN2 | |
| SCHEMBL11369241 | 0.85 | CYP2D6 (0.97) | CYP2D6CYP2C9HIF1APRMT6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655595-A | 2, 6-piperidinedione derivatives, their preparation and use | 中国人民解放军军事科学院军事医学研究院 | 2023-08-29 | — | — | CN | disclosed |