Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 14/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 14/20 | 0.41 |
| ▸ | CDK2 | P24941 | 11/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20542038 | 1.00 | CDK5 (0.41) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL30579323 | 0.85 | CDK2 (0.53) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL24966401 | 0.83 | CDK5 (0.42) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL2311254 | 0.79 | CDK2 (0.54) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL31707890 | 0.74 | CDK2 (0.49) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL1293109 | 0.74 | CDK2 (0.49) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL24966413 | 0.74 | CDK2 (0.38) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL21754116 | 0.73 | CDK2 (0.38) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL2315103 | 0.73 | AHR (0.58) | CDK5CDK5R1CDK2CCNA2CCNA1 | |
| SCHEMBL2313618 | 0.72 | CDK1 (0.47) | CDK5CDK5R1CDK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |