Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069764 | 0.84 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL3063507 | 0.84 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL3065399 | 0.84 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL3068282 | 0.84 | KDM4E (0.39) | KDM4EHTT | |
| SCHEMBL3062297 | 0.82 | HTT (0.39) | KDM4EHTT | |
| SCHEMBL3052347 | 0.81 | KDM4E (0.37) | KDM4EHTT | |
| SCHEMBL5012158 | 0.79 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL5011042 | 0.79 | KDM4E (0.34) | KDM4EHTT | |
| SCHEMBL3067923 | 0.79 | KDM4E (0.39) | KDM4EHTT | |
| SCHEMBL5011046 | 0.79 | KDM4E (0.34) | KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261719-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | US | disclosed |
| EP-2193132-A2 | 3-SPIROPYRIMIDINETRIONE-QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | AstraZeneca AB (SE) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009004382-A2 | 3-SPIROPYRIMIDINETRIONE-QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261719-A1 | CHEMICAL COMPOUNDS | NCOA3, NR4A3, NR0B2 | KDM4E 4486/4885HTT 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.